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. 2019 Feb 25;4(1):56–71. doi: 10.1016/j.jacbts.2018.10.004

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Functional Outcomes of Bioactive IL-4 Surfaces In Vivo

(A) Measurement of fibrotic capsule formation/thickness at the implant surface (top). (B) Representative hematoxylin and eosin (H&E) stains of fibrotic capsules. (C) Quantification of collagen deposition at the implant surface. (D) Representative trichrome stains of collagen (green) within the fibrotic capsule, highlighted by arrows. Dotted lines represent the interface between tissue (above) and implant (below). Scale bar represents 50 μm, n = 5 per group. IL-4 = interleukin 4.