Figure 8.

Functional Outcomes of Bioactive IL-4 Surfaces for Synthetic Vascular Grafts

(A) Quantification of adventitia capsule thickness. (B) Quantification of neointimal hyperplasia development along 3 segments of vascular graft lumen. (C) Representative images of capsule thickness on the adventitia of vascular grafts, scale bar represents 150 μm; representative magnified images of vascular graft lumens (inset). Scale bar represents 40 μm. Dotted lines represent the luminal edge of hyperplasia, and solid lines represent the luminal graft surface. n = 3 slides (each region of the graft) per animal with the average represented as the red dotted line; total of n = 5 animal averages per group. IL-4 = interleukin 4.