Table 2.

Differences in the exosomal protein profiles among the disease categories detected by 2D-DIGE

A. wRA vs. HL
Total number of detected protein spots	Number of spots with different intensities (p < 0.05)	fold difference (wRA/HL)	number of spots
204	28	X ≥ 1.3	5
		1.3 > X > −1.3	21
		−1.3 ≥ X	2
B. aRA vs. HL
Total number of detected protein spots	Number of spots with different intensities (p < 0.05)	fold difference (aRA/HL)	number of spots
204	31	X ≥ 1.3	13
		1.3 > X > −1.3	7
		− 1.3 ≥ X	11
C. iRA vs. HL
Total number of detected protein spots	Number of spots with different intensities (p < 0.05)	fold difference (iRA/HL)	number of spots
204	14	X ≥ 1.3	1
		1.3 > X > −1.3	9
		−1.3 ≥ X	4
D. OA vs. HL
Total number of detected protein spots	Number of spots with different intensities (p < 0.05)	fold difference (OA/HL)	number of spots
204	21	X ≥ 1.3	1
		1.3 > X > −1.3	14
		−1.3 ≥ X	6

wRA whole RA, aRA active RA, iRA inactive RA, OA osteoarthritis, HL healthy donor