Table 1.
Baseline characteristics of included patients.
|
Patients with CAD (n = 74) |
Patients with ACAO (n = 92) |
Patients without CAD or ACAO (n = 1398) |
P-value CAD vs. ACAO |
P-value CAD vs. without CAD or ACAO |
|
|---|---|---|---|---|---|
| Sex-male (%) | 55 (74.3) | 72 (78.3) | 727 (52.0) | 0.69 | <0.001 |
| Age-years (median [IQR]) | 52 [45–59] | 68 [58–77] | 71 [60–80] | <0.001 | <0.001 |
| Smoking (%) | 21 (28.4) | 36 (39.6) | 313 (22.5) | 0.18 | 0.31 |
| Diabetes mellitus (%) | 2 (2.7) | 15 (16.7) | 228 (16.4) | 0.01 | 0.01 |
| Atrial fibrillation (%) | 7 (9.6) | 3 (3.3) | 344 (24.9) | 0.17 | 0.01 |
| Hypertension (%) | 18 (24.3) | 38 (41.8) | 704 (51.0) | 0.03 | <0.001 |
| Myocardial infarction (%) | 2 (2.7) | 12 (13.2) | 224 (16.3) | 0.04 | 0.01 |
| Previous stroke (%) | 6 (8.3) | 7 (7.6) | 241 (17.3) | 1.00 | 0.07 |
| Hypocholesteremia (%) | 5 (6.8) | 19 (21.1) | 418 (30.8) | 0.02 | <0.001 |
| Pre-stroke independence (mRS ≤ 2) (%) | 70 (95.9) | 90 (98.9) | 1221 (88.6) | 0.46 | 0.08 |
| Stroke severity at baseline (NIHSS) (median [IQR])a | 16 [12–19] | 16 [11–19] | 16 [12– 20] | 0.43 | 0.81 |
| Location intracranial occlusion (%) | 0.42 | <0.001 | |||
| Other | 0 (0.0) | 0 (0.0) | 11 (0.8) | ||
| Intracranial ICA | 16 (22.2) | 17 (18.7) | 46 (3.4) | ||
| ICA-T | 25 (34.7) | 33 (36.3) | 298 (21.9) | ||
| M1 | 26 (36.1) | 39 (42.9) | 828 (60.8) | ||
| M2 | 5 (6.9) | 2 (2.2) | 178 (13.1) | ||
| ASPECTS score at baseline (median [IQR])b | 8 [7–10] | 8 [7–9] | 9 [7–10] | 0.57 | 0.23 |
| Collateral grading score (%)c | 0.14 | 0.36 | |||
| 0 | 2 (2.9) | 1 (1.1) | 94 (7.0) | ||
| 1 | 28 (40.0) | 27 (29.7) | 435 (32.5) | ||
| 2 | 27 (38.6) | 32 (35.2) | 516 (38.5) | ||
| 3 | 13 (18.6) | 31 (34.1) | 294 (22.0) | ||
| Treatment with intravenous thrombolysis (%) | 63 (85.1) | 79 (85.9) | 1086 (77.7) | 1.00 | 0.17 |
| Duration from stroke onset to groin puncture (median [IQR]) | 235 [173–295] | 211 [178–271] | 210 [160–270] | 0.54 | 0.15 |
a
National Institute of Health Stroke scale (Scores range from 0 to 42, higher scores indicating severe stroke).
b
Alberta Stroke Program Early Computed tomography Score (Scores range from 0 to 10 lower scores indicating more early ischemic changes on baseline NCCT).
c
Assessed at baseline CTA. A score of 0 indicated absent collateral supply to the occluded territory, 1: filling of >0% but ≤50%, 2: filling of >50% but <100%, 3: filling of 100% collateral supply of the occluded territory.