Table 1. Demographic data and baseline tumour characteristics.
ROS1 positive number (%) | ROS1 negative number (%) | |
---|---|---|
Number of patients | 22 | 513 |
Median age | 54 | 60 |
Gender | ||
• Male | 13 (60%) | 372 (72%) |
• Female | 09 (40%) | 141 (28%) |
Smoking history | 03 (13%) | 240 (47%) |
Co-morbidities | ||
• Hypertension | 07 (31%) | 123 (24%) |
• Diabetes Mellitus | 04 (18%) | 95 (18%) |
Stage of disease | ||
• Stage III | 1 (5%) | 22 (4%) |
• Stage IV | 21 (95%) | 491 (96%) |
Median number of metastatic sites | 2 | 2 |
• Opposite lung | 11 (50%) | 265 (52%) |
• Brain metastasis | 2 (9%) | 71 (14%) |
• Pleural effusion | 9 (40%) | 231 (45%) |
• Liver | 2 (9%) | 70 (14%) |
• Adrenals | 6 (27%) | 51 (10%) |
• Bones | 8 (36%) | 154 (30%) |
Procurement of crizotinib n = 16 | ||
Self, no insurance | 7 (44%) | |
Self, insurance | 4 (25%) | |
Sponsored by NGO | 5 (31%) |