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. Author manuscript; available in PMC: 2019 Feb 26.
Published in final edited form as: Toxicology. 2018 Jul 25;409:24–32. doi: 10.1016/j.tox.2018.07.007

Fig. 3. Tumor number per mouse lung and tumor multiplicity upon gross examination in A/J mice following initiation-promotion study at 30 week sacrifice.

Fig. 3.

MCA initiation followed by GMAW-MS fume inhalation significantly increased lung tumor multiplicity compared to MCA/air (21.86 ± 1.50 vs 8.34 ± 0.59, respectively). As expected, mice not initiated with MCA had low tumor numbers. Horizontal bars represent mean tumor numbers per group. Circles = CO/air, squares = CO/GMAW-MS, upward triangles = MCA/air, downward triangles = MCA/GMAW-MS. *p < 0.0001 – compared to CO/air; **p < 0.0001 – compared to MCA/air.