Table 3.
Total and means ± standard error () tumor number in A/J mice across each of the individual lung lobes following GMAW-MS fume or air whole-body inhalation exposure 30 weeks post-initiation with MCA or corn oil.
n | Left | Apical | Cardiac | Diaphragmatic | Azygos | |
---|---|---|---|---|---|---|
CO/air | 29 | 4 (0.14 ± 0.07) | 2 (0.07 ± 0.05) | 0 | 1 (0.03 ± 0.03) | 1 (0.03 ± 0.03) |
CO/GMA-MS | 28 | 3 (0.12 ± 0.06) | 0 | 0 | 1 (0.04 ± 0.04) | 1 (0.04 ± 0.04) |
MCA/air | 29 | 81 (2.79 ± 0.32)** | 28 (0.97 ± 0.16)** | 37 (1.28 ± 0.24)** | 67 (2.31 ± 0.29)** | 29 (1.00 ± 0.16)** |
MCA/GMA-MS | 28 | 226 (8.07 ± 0.74)* | 77 (2.75 ± 0.31)* | 77 (2.75 ± 0.36)* | 187 (6.68 ± 0.48)* | 45 (1.61 ± 0.28)^ |
Abbreviations: CO- corn oil; GMAW-MS- gas metal arc welding – mild steel; MCA-3-methylchloanthrene.
p < 0.0001 - compared to MCA/air
p < 0.0001 - compared to CO/air
p < 0.04 - compared to MCA/air.