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. 2019 Feb 22;14:1451–1467. doi: 10.2147/IJN.S193544

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© 2019 Xin et al. This work is published and licensed by Dove Medical Press Limited

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Relative gene expression of osteogenic markers.

Notes: BMSCs were cultured with the different extracts of i/SCS/P for 3 and 7 days, respectively. BMSCs cultured with the extracts of SCS/P scaffolds were used as control. Relative gene expressions of RUNX-2, ALP, Osterix, BMP2, OCN, and OPN were determined by PCR. *P<0.05, compared with the corresponding control group.

Abbreviations: BMSCs, bone marrow stem cells; i/SCS/P, irisin-loaded silk/calcium silicate/sodium alginate/PVA; SCS/P, silk/calcium silicate/sodium alginate/PVA.