Table 3.
Characteristics of NPC patients treated with NACT + IMRT + CCRT vs NACT + IMRT
| Total (n=l25) | NACT + IMRT (n=36) | NACT + IMRT + CCRT (n=89) | |
|---|---|---|---|
|
| |||
| Characteristics | Cases (%) | Cases (%) | Pa (Pearson’s χ2) |
|
| |||
| Age of diagnosis | 0.296 | ||
| <55 | 16 (12.8) | 46 (36.8) | |
| ≥55 | 20 (16.0) | 43 (34.4) | |
| Gender | 0.429 | ||
| Female | 13 (10.4) | 29 (23.2) | |
| Male | 23 (18.4) | 60 (48.0) | |
| Smoking history | 0.162 | ||
| Never | 22 (17.6) | 44 (35.2) | |
| Ever | 14 (11.2) | 45 (36.0) | |
| Alcohol use | 0.454 | ||
| Never | 23 (17.2) | 58 (48.5) | |
| Ever | 13 (6.1) | 31 (28.3) | |
| Family history | 0.525 | ||
| No | 30 (18.4) | 57 (46.4) | |
| Yes | 6 (10.4) | 32 (24.8) | |
| WHO histology | 0.603 | ||
| II | 6 (4.8) | 15 (12.0) | |
| III | 30 (24.0) | 74 (59.2) | |
| AJcc stage | 0.319 | ||
| III | 22 (17.6) | 60 (48.0) | |
| IVA + IVB | 14 (11.2) | 29 (23.2) | |
| T stage | 0.276 | ||
| T1–2 | 11 (8.8) | 34 (27.2) | |
| T3–4 | 25 (20.0) | 55 (44.0) | |
| N stage | 0.153 | ||
| N0–1 | 17 (13.6) | 29 (23.2) | |
| N2–3 | 19 (15.2) | 60 (48.0) | |
| courses of NAcT | |||
| I | 4 (3.2) | 9 (7.2) | 0.548 |
| 2–4b | 32 (25.6) | 80 (60.0) | |
Notes:
a
Two-sided chi-squared test.
b
Only two patients receive four courses of NACT.
Abbreviations: AJCC, American Joint Committee on Cancer; CCRT, concurrent chemotherapy; IMRT, intensity modulated radiotherapy; NACT, neoadjuvant chemotherapy; NPC, nasopharyngeal carcinoma.