Table 6.

Multivariate analysis of prognostic factors

Items	3-year OS		3-year LRFS		3-year DMFS		3-year PFS
	%	P-value	%	P-value	%	P-value	%	P-value
Age (years)		0.872		0.484		0.538		0.347
<55	89.2		94.7		83.4		77.2
≥55	87.6		92.8		81.2		75.4
Gender		0.596		0.287		0.773		0.457
Male	89.3		93.9		83.8		77.5
Female	87.7		93.2		81.2		75.8
T stage		0.092		0.005*		0.574		0.060
T1-2	89.8		94.8		82.1		77.9
T3-4	87.5		92.1		82.8		75.8
N stage		0.002*		0.001*		0.032*		0.001*
N0-1	92.4		95.6		84.7		78.8
N2-3	83.5		91.8		80.2		74.6
Smoking		0.691		0.554		0.428		0.337
Never	89.6		91.2		83.5		77.8
Ever	86.8		95.4		81.6		76.0
Alcohol use		0.769		0.443		0.352		0.287
Never	88.2		92.8		81.4		75.7
Ever	89.4		94.5		83.6		77.9
Use of CCRT		0.114		0.124		0.668		0.475
No	89.4		91.7		83.3		77.8
Yes	88.5		94.4		82.0		76.1
GTVnx volume (cm3)		0.438		0.473		0.040*		0.145
<40	89.1		93.2		84.8		77.5
≥40	87.7		93.9		80.1		76.2

Note:

^*P<0.05.

Abbreviations: CCRT, concurrent chemoradiotherapy; DMFS, distant metastasis-free survival; LRFS, local relapse-free survival; OS, overall survival; PFS, progression-free survival.