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. 2019 Feb 13;15(2):e1007598. doi: 10.1371/journal.ppat.1007598

Table 1. Susceptibilities of wild-type Bristol N2 strain and individual NHRs loss-of-function Caenorhabditis elegans mutants to IVM.

Strain EC50 IVM (nM)
Bristol N2 1.63 ± 0.29
AE501, nhr-8(ok186) 0.96 ± 0.12 ***
AA107, nhr-48(ok178) 1.62 ± 0.14
DR20, daf-12(m20) 1.67 ± 0.17

EC50 (effective concentration for 50% inhibition) calculated from Larval Development Assay.

*** p<0.001 vs Bristol N2