Figure 2. Anti-rhFLSC responses were not effectively elicited 21 weeks (3 weeks after the last vaccination) after intrarectal immunization with rhFLSC plus cholera toxin (CT) in the plasma of the macaques in the second study.

(A and B) The immunization groups (A) and protocol (B) of the 30 macaques. (C) Only marginal anti-rhFLSC responses (IgG) were induced at the highest CT dose and no detectable responses at the lower doses of CT. (D) Anti-CT antibody responses (IgG) were elicited in a dose-dependent fashion.