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. 2019 Feb 11;129(3):1180–1192. doi: 10.1172/JCI122694

Figure 10. Evidence for an ETV2/GATA-2 regenerative axis.

Figure 10

(A) ETV2 ChIP-Seq. ETV2 occupancy was detected at the +9.5 enhancer in mouse embryonic stem cell–derived embryoid bodies (GEO GSE59402) (41). (B) Sorted LSK cells from WT (n = 6) or Tie2-Cre Etv2 conditional–knockout mice (n = 6) 10 days after 5-FU injection (250 mg/kg). Gata2 mRNA levels were normalized to Actb. **P < 0.01, by 2-tailed, unpaired Student’s t test.