(A) Multilineage repopulating activity 16 weeks after competitive transplantation (n = 10 per genotype). *P < 0.05 and ***P < 0.001, by 2-tailed, unpaired Student’s t test. (B) Analysis of donor-derived LSK cells, HSCs, MPPs, LS–K cells, CMPs, GMPs, and MEPs in BM 16 weeks after competitive transplantation (n = 10 per genotype). Statistical significance was determined by 2-tailed, unpaired Student’s t test.