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. 2019 Feb 19;14:1299–1309. doi: 10.2147/IJN.S188049

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© 2019 Zhao et al. This work is published and licensed by Dove Medical Press Limited

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The relative expression of Per2, Bax, and Bcl-2 mRNA in A549-transplanted null mice after PTX-NPs treatment at 0, 5, 10, 15, and 20 HALO in vivo.

Notes: (A) The relative mRNA level of Per2; (B) The relative mRNA level of Bax; (C) The relative mRNA level of Bcl-2. Compared to control, ^*P<0.05, and ^**P<0.01; compared to PTX, ^#P<0.05. Mice treated with saline were used as controls.

Abbreviations: HALO, hours after light onset; PTX, paclitaxel; PTX-NPs, paclitaxel nanoparticles.