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Factors and responses used in Scheffé’s mixture design
| Factors | Range | |
|---|---|---|
| Low limit (w/w %) | High limit (w/w %) | |
| X1: Capmul MCM (oil) | 10 | 40 |
| X2: Cremophor EL (surfactant) | 10 | 80 |
| X3: Transcutol P (cosurfactant) | 10 | 80 |
| Responses | Goal | |
| Y1: Solubility (mg/mL) | Maximize | |
| Y2: Precipitation (%) | Minimize | |
| Y3: Droplet size (nm) | Minimize | |
| Y4: Transmittance (%) | Maximize | |
