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. 2019 Feb 15;14:1193–1212. doi: 10.2147/IJN.S190426

Table 4.

Predicted values and actual values of optimized TCG-SM

Optimized factors Response Goal Importance 95% Cl low predicted value Predicted value 95% Cl high predicted value Actual value Error percentage (%)
X1: 10.0%
X2: 53.8%
X3: 36.2%
Y1: Solubility (mg/mL) Maximize +++ 212.01 222.32 232.62 236.2±3.6 6.25
Y2: Precipitation (%) Minimize +++ −4.0 10.4 24.7 10.6±0.3 2.50
Y3: Droplet size (nm) Minimize +++ 25.6 116.7 207.8 110.2±2.6 5.61
Y4: Transmittance (%) Maximize +++ 90.7 95.3 99.8 96.6±0.2 1.36

Note: Values are expressed as mean ± SD (n=3).

Abbreviations: TCG-SM, ticagrelor-loaded self-microemulsifying drug delivery system; CI, confdence interval.