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. 2019 Feb 18;14:1255–1268. doi: 10.2147/IJN.S191858

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© 2019 Tan et al. This work is published and licensed by Dove Medical Press Limited

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The cellular uptake and intracellular distribution of Dox and FAM-siRNA in H22 cells after being treated with free Dox, Dox-LPs, Dox-TPGS-LPs, or FAM-siRNA/Dox-TPGS-LPs (Dox, 5 µg/mL) for 4 hours.

Notes: Blue DAPI staining indicates the nucleus, and green FAM indicates siBcl-2 in the images. Scale bars represent 10 µm.

Abbreviations: Dox, doxorubicin; FAM, fluorescein amidite; LPs, liposomes; siBcl-2, Bcl-2 siRNA; TPGS, D-α-tocopherol polyethylene glycol 1000 succinate.