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. 2019 Feb 18;14:1255–1268. doi: 10.2147/IJN.S191858

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© 2019 Tan et al. This work is published and licensed by Dove Medical Press Limited

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The cytotoxicity of the various formulations against H22 cells at the designed Dox concentrations after 24 hours.

Note: The IC₅₀ of free Dox, Dox-LPs, Dox-TPGS-LPs, and siBcl-2/Dox-TPGS-LPs was 2.73, 0.83, 0.81, and 0.35 µg/mL, respectively.

Abbreviations: Dox, doxorubicin; IC₅₀, half-maximal inhibitory concentration; LPs, liposomes; siBcl-2, Bcl-2 siRNA; TPGS, D-α-tocopherol polyethylene glycol 1000 succinate.