Skip to main content
. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Hum Genet. 2018 Feb 9;137(3):231–246. doi: 10.1007/s00439-018-1874-3

Figure 7. CASKG659D but not CASKW919R disrupts CASK-neurexin interaction.

Figure 7.

Images of HEK293FT cells transfected with GFP-CASKW919R or GFP-CASKG659D plasmid DNA co-expressed with neurexin-1β-FLAG (A,B). After 48 hours, cells were fixed, permeabilized and immunostained for neurexin. Scale bar = 5μm. C) Co-localization analysis of neurexin and CASK performed from 22 different images collected from 3 separate experiments. Results are plotted as mean±SD. * indicates p < 0.05.