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. 2019 Jan 3;96(1):38–48. doi: 10.1007/s11524-018-00329-x

Table 4.

Diagnosis codes that are more likely during ED/hospital visits of decedents with opioid prescription history than of decedents with no opioid prescription history

ICD-10 code Description Percentage of visits with diagnosis Difference (%)
Any opioid analgesic prescription
Yes No
I10 Essential (primary) hypertension 19.1 12 − 7***
G8929 Other chronic pain 7.2 0.9 − 6.3***
M545 Low back pain 5.5 1.2 − 4.2***
M549 Dorsalgia, unspecified 4.8 0.8 − 4***
F419 Anxiety disorder, unspecified 11.3 7.6 − 3.7**
M5489 Other dorsalgia 3.8 0.6 − 3.2***
K219 Gastro-esophageal reflux disease without esophagitis 4.7 1.7 − 3***
Z79891 Long-term (current) use of opiate analgesic 6.8 3.8 − 3***
E785 Hyperlipidemia, unspecified 4.2 1.3 − 2.9***
E119 Type 2 diabetes mellitus without complications 4.7 1.9 − 2.8***
F319 Bipolar disorder, unspecified 5.5 2.7 − 2.8***
J449 Chronic obstructive pulmonary disease, unspecified 4.6 1.8 − 2.8***
I2510 Atherosclerotic heart disease of the native coronary artery without angina pectoris 2.9 0.5 − 2.4***
E784 Other hyperlipidemia 2.8 0.7 − 2.1***
I509 Heart failure, unspecified 2.2 0.6 − 1.6***
Z8673 Personal history of transient ischemic attack (TIA) and cerebral infarction without residual deficits 2.1 0.6 − 1.5**
Z7982 Long-term (current) use of aspirin 1.9 0.5 − 1.4*

Note. Columns “Yes” and “No” contain the percentage of all visits in each group that carried each ICD-10 code. The p values are Bonferroni-corrected p values calculated using Fisher’s exact test

*p < .05; **p < .01; ***p < .001