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FGF21 decreases hypoxia-induced MMP activities in CMEC. (A,B) Quantitative analyses on the activities of MMP-3 (A) and MMP-2/9 (B) in CMECs under the condition of normoxia and hypoxia (1% O2) with FGF21 treatment (50 nM) or vehicle for 8 h. *p < 0.05, **p < 0.01 vs. Veh. N = 8. Veh, vehicle. For N = 8, experiments were conducted in eight different wells of cultured cells.
