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. 2019 Feb 20;10:101. doi: 10.3389/fphar.2019.00101

Figure 6.

Figure 6

Blockade of HSP72 by chemical inhibitor compromises the protection of FGF21 against hypoxia in CMECs. (A,B) The mRNA (A) and protein (B) levels of HSP72 in CMECs under the condition of normoxia and hypoxia (1% O2) with FGF21 treatment (50 nM) or vehicle for 8 h. *p < 0.05. N = 8. (C,D) The cell viability (C) and LDH release (D) of CMECs under the condition of normoxia and hypoxia (1% O2) with FGF21 treatment (50 nM) or FGF21 + VER155008 (50 μM) or vehicle for 8 h. *p < 0.05. N = 8. Veh, vehicle. For N = 8, experiments were conducted in eight different wells of cultured cells.