Table 1.

microRNAs associated with hypoxia and the stem-like state in four aggressive cancers.

Cancer	Hypoxia	Stem-like state	Reference
Glioblastoma	miR-205-5p, miR-210, miR-21-5p miR-23b- 3p, miR-7-5p	miR-125b, miR-33a, miR-34 miR-10b, miR-143, miR-330, miR-582-5p, miR-363, miR-138, miR-153, miR-124, miR-9, miR-128 miR-218, miR-146-a miR-326	Godlewski et al., 2008; Kefas et al., 2009; Li Y. et al., 2009; Li Z. et al., 2009; Guessous et al., 2010, 2013; Shi et al., 2010; Mei et al., 2011; Chan et al., 2012; Chen L. et al., 2012; Yue et al., 2012; Tan et al., 2012; Lee et al., 2013; Qiu et al., 2013; Tu et al., 2013; Zhao et al., 2013a,b; Babae et al., 2014; Floyd et al., 2014; Lai et al., 2014; Wang H. et al., 2014; Yao et al., 2014; Zhang et al., 2014
Cervical cancer	miR-152, miR-210	miR-23b, miR-125b	(Phuah et al., 2017; Tang et al., 2016)(Wang et al., 2013, 2017; Zhou X. et al., 2017)
Prostate cancer	miR-301a/b, miR-517a, miR 204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-181a miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491	miR-141, miR-1301-3p, miR, 150, miR-574	Liu et al., 2015; Liu C. et al., 2017; Chen et al., 2016; Wang W. et al., 2016; Panigrahi et al., 2018; Song et al., 2018
Breast cancer	miR-210, miR-155	miR-590-5p, miR-181a-5p, miR-30e-5p, miR-34	Choi et al., 2011; Kong et al., 2014; Rupaimoole et al., 2016; Liu K. et al., 2017; Zhou L. et al., 2017

Several microRNAs have been associated with the hypoxia microenvironment and the cancer stem-like state. Their roles are not fully understood but they all play roles that favor the tumor aggressiveness. miR, microRNAs.