Table 3.
Decreased functional connectivity of the insula subdivisions in SNHL subjects comparing with Controls.
| Brain region | BA | Side | MNI coordinate | Peak t-value | Cluster size | ||
|---|---|---|---|---|---|---|---|
| X | Y | Z | |||||
| Functional connectivity of left vAI | |||||||
| Thalamus | – | R | 12 | -22 | 9 | -7.2482 | 102 |
| Thalamus | – | L | -6 | -18 | 6 | -6.736 | 57 |
| Precentral gyrus | 6 | R | 42 | -12 | 45 | -6.3206 | 68 |
| Functional connectivity of left dAI | |||||||
| Thalamus | – | R | 6 | -21 | 9 | -7.6285 | 298 |
| Putamen | 48 | R | 30 | -3 | 9 | -5.8026 | 81 |
| Dorsolateral prefrontal cortex | 46 | R | 42 | 42 | 27 | -5.3125 | 53 |
| Precentral gyrus | 6 | R | 42 | -12 | 45 | -6.227 | 303 |
| Mid-cingulate cortex | – | R | 15 | -36 | 39 | -5.522 | 53 |
| Postcentral gyrus | 6 | R | 27 | -27 | 66 | -5.3037 | 62 |
| Functional connectivity of right dAI | |||||||
| Rolandic operculum | 48 | R | 39 | -12 | 21 | -5.8744 | 56 |
| Functional connectivity of right PI | |||||||
| Thalamus | – | L | 9 | -21 | 9 | -6.4883 | 108 |
| Precentral gyrus | 6 | R | 39 | -12 | 45 | -6.4082 | 229 |
The threshold was set at p < 0.001, false discovery rate correction. BA, Brodmann area; vAI, ventral anterior insula; dAI, dorsal anterior insula; PI, posterior insula.