. 2019 Feb 26;9:2762. doi: 10.1038/s41598-019-39324-w

Table 3.

Antibiofilm effect of TPU and PDMS composites.

Species	Time (days)	Reduction in initial biofilm cell burden (in percentage, %RBB)^*
		TPU composites					PDMS composites
		P5	P15	P25	P35	P50	S5	S15	S25	S35	S50
S. epidermidis	2	64.1 ± 25.1	64.4 ± 32.9	86.3 ± 14.7^a	97.0 ± 1.3^a	97.7 ± 2.0^a	76.2 ± 25.8	83.3 ± 11.7	83.8 ± 17.5	92.4 ± 8.8^a	98.5 ± 0.9^a
S. epidermidis	5	67.9 ± 10.3	87.8 ± 3.7^a	98.7 ± 0.4^a,c	99.1 ± 0.2^a,c	98.9 ± 0.3^a,c	89.5 ± 10.8	92.5 ± 0.4^a	93.4 ± 3.6^a	95.6 ± 0.9^a	96.0 ± 4.3^a
S. aureus	2	67.9 ± 16.5	72.9 ± 20.2	62.8 ± 32.9	72.4 ± 28.4	79.6 ± 1.3^a	20.6 ± 11.7	20.4 ± 2.5	30.5 ± 6.6	22.5 ± 1.9	24.9 ± 6.7
S. aureus	5	61.6 ± 5.2	86.0 ± 6.9^a	92.4 ± 0.2^a	95.6 ± 3.1^a,c	97.9 ± 1.7^a,b,c	30.1 ± 5.3	78.0 ± 4.4	85.0 ± 2.1^a	90.2 ± 4.1^a,b	94,3 ± 4.1^a,b
E. coli	2	42.6 ± 11.6	60.2 ± 39.7	47.8 ± 19.6	39.1 ± 46.2	47.6 ± 26.7	46.2 ± 13.6	54.7 ± 2.4	60.8 ± 11.9	57.8 ± 16.5	66.9 ± 10.0
E. coli	5	84.4 ± 4.4^a	88.5 ± 7.1^a	90.9 ± 5.9^a,b	87.0 ± 13.6^a,b	95.2 ± 4.8^a,b	88.3 ± 5.5^a	92.6 ± 7.5^a,b	89.9 ± 0.8^a,b	95.1 ± 1.7^a,b	92.0 ± 2.1^a,b
P. aeruginosa	2	46.8 ± 19.6	45.7 ± 33.3	59.9 ± 37.0	79.6 ± 0.8^a	80.6 ± 8.9^a	—	—	—	—	—
P. aeruginosa	5	77.5 ± 26.0	76.1 ± 19.1	72.9 ± 17.8	83.7 ± 1.9^a	93.8 ± 3.7^a	34.7 ± 38.9^b	23.9 ± 48.5^b	—	—	—

^acounts significantly lower than untreated polymers (p < 0.01).

^bincrease in the antibiofilm activity on day 5 vs. day 2 (p < 0.01).

^csignificantly more active than composites with 5 wt% of glass content.

^*%RBB are calculated as the mean (±SD) reduction for each species (2 strains of S. epidermidis, 2 strains of S. aureus, 2 strains of E. coli and 2 strains of P. aeruginosa).