Table 1.
Drug-sensitivities correlated with integrin α3 (ITGα3) expression levels in the CCLE databases.
| Drug name | correlation | average | variation | N |
|---|---|---|---|---|
| Paclitaxel | −0.136521 | 0.7962 | 0.1585 | 28 |
| RAF-265 | −0.194086 | 0.8281 | 0.1089 | 23 |
| 17-AAG | 0.007134 | 0.7962 | 0.1585 | 28 |
| Irinotecan | −0.131134 | 0.8285 | 0.1199 | 19 |
| Lapatinib | 0.111679 | 0.7962 | 0.1585 | 28 |
| Panobinostat | −0.165702 | 0.7962 | 0.1585 | 28 |
| TKI258 | −0.400488 | 0.7962 | 0.1585 | 28 |
| Topotecan | 0.166555 | 0.7962 | 0.1585 | 28 |
| L-685458 | −0.193066 | 0.7962 | 0.1585 | 28 |
| PD-0332991 | −0.161663 | 0.8295 | 0.1112 | 22 |
| PF2341066 | −0.020896 | 0.7962 | 0.1585 | 22 |
| Erlotinib | −0.052117 | 0.7962 | 0.1585 | 28 |
| AZD0530 | −0.273753 | 0.7962 | 0.1585 | 28 |
| LBW242 | −0.049073 | 0.7962 | 0.1585 | 28 |
| TAE684 | −0.02831 | 0.7962 | 0.1585 | 28 |
| ZD-6474 | 0.353902 | 0.7899 | 0.1580 | 28 |
| PHA-665752 | −0.379134 | 0.7962 | 0.1685 | 28 |
| AZD6244 | 0.20628 | 0.7962 | 0.1585 | 28 |
| PD-0325901 | −0.070893 | 0.7962 | 0.1585 | 22 |
| Sorafenib | −0.220974 | 0.7962 | 0.1585 | 28 |
| Nilotinib | −0.07676 | 0.8290 | 0.1140 | 21 |
| Nutlin-3 | 0.109441 | 0.7962 | 0.1585 | 28 |
| PLX4720 | −0.253 | 0.7899 | 0.1585 | 27 |
| AEW541 | −0.259067 | 0.7962 | 0.1585 | 28 |
Correlation of sensitivities to various anti-cancer drugs with ITGα3 expression levels in different pancreatic cancer cells.
ƗN indicates the number of human pancreatic cancer cell lines.