Table 2.
Kinetics of CF- and PF-EPSCs.
| Control | n | PC-mTOR Tg | n | p value | ||
|---|---|---|---|---|---|---|
| CFs mono & multi-S |
Amplitude (pA) | 1605 ± 70 | 32 | 2745 ± 185 | 21 | <0.001 |
| Rise time (ms) | 0.51 ± 0.02 | 32 | 0.62 ± 0.03 | 19 | <0.001 | |
| τdecay (ms) | 8.89 ± 0.22 | 32 | 4.85 ± 0.31 | 19 | <0.001 | |
| Paired-pulse ratio | 0.71 ± 0.01 | 32 | 0.67 ± 0.02 | 21 | 0.051 | |
| PFs | Paired-pulse ratio | 1.74 ± 0.03 | 39 | 1.65 ± 0.06 | 14 | 0.115 |
Statistical analyses were performed as follows; Mann-Whitney Rank Sum test for Amplitude, Rise time and Paired-pulse ratio; Student t-test for τdecay. Kinetics and paired-pulse ratio of CF-EPSCs were measured from CFs sampled from mono-innervated Purkinje cells (mono) and CFs with the largest EPSC amplitude in multiply-innervated Purkinje cells (multi-S).