Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 26;9:2749. doi: 10.1038/s41598-019-39067-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

S100A8 and S100A9 transcripts are diagnostic and poor prognostic markers for GBM. (A) ROC curve depicting transcript levels of S100A8 and S100A9 discriminate between control and GBM, AUC and p value is indicated. (B) ROC curve depicting transcript levels of S100A8 and S100A9 discriminate between grade III and GBM, AUC and p value is indicated. (C) ROC curve depicting transcript levels of S100A8 and S100A9 discriminate mesenchymal subtype from other GBM subtypes, AUC and p value is indicated. (D) Univariate and Multivariate cox proportional hazard regression analysis was performed using TCGA Affymetrix data for transcript levels of S100A8 and S100A9 along with age, G-CIMP status, IDH1 mutation status, MGMT promoter methylation status. (E,F) Kaplan Meier survival analysis using TCGA Affymetrix cohort (n = 518) for transcript levels of S100A8 and S100A9. Log-rank (Mantel–Cox) test was applied and the p value is indicated.