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. 2019 Feb 6;6(3):e154–e166. doi: 10.1016/S2352-3026(18)30220-5

Figure 1.

Figure 1

Non-intensive pathways of the NCRI Myeloma XI and MRC Myeloma IX studies

Standard genetic risk defined as the absence of any of the risk lesions t(4;14), t(14;26), t(14;20), del(17p) and gain(1q); high genetic risk defined as the presence of at least one of these lesions. CRDa=attenuated cyclophosphamide, lenalidomide, and dexamethasone. CRP=C-reactive protein. CTDa=attenuated cyclophosphamide, thalidomide, and dexamethasone. CVD=cyclophosphamide, bortezomib, and dexamethasone. ISS=International Staging System. MP=melphalan and prednisolone. MRC-IX=MRC Myeloma IX. NCRI-XI=NCRI Myeloma XI. QoL=quality of life.