Figure 2.

Stroke accelerates action potential maturation in DCX⁺ ABGCs. A, Representative voltage responses of granule cells to 300 ms stepwise current injections (calibration: top, 5 ms, 20 mV; bottom, 50 ms, 40 mV). B, Histograms of maximal AP rise show faster APs after MCAO in DCX⁺ ABGCs, but no change in DCX⁻ neurons after stroke. C, Based on maximal AP rise, cells could be classified into the following three groups: immature, intermediate, and mature APs (right, classification criteria). There was a higher proportion of mature APs after MCAO in DCX⁺ neurons, but the distributions did not change after MCAO. D, Phase plots of action potentials of all cells in the examined groups. Each trace represents one cell. Dashed horizontal lines represent the limits of immature, intermediate and mature AP (see above). See also Table 2 for statistical results.