Table 1.

Demographic and clinical data

	CIS n = 31	RRMS n = 416	SPMS n = 84	PPMS n = 73	All patients n = 642
Gender, female / male	22 / 10	293 / 150	49 / 34	39 / 36	411 / 231
Age, years, mean ± SD	43.1 ± 11.0	43.2 ± 8.2	54.0 ± 8.9	57.5 ± 12.0	44.3 ± 13.0
Disease duration, years, mean ± SD	4.2 ± 3.7	8.9 ± 8.2	23.4 ± 10.7	16.6 ± 9.9	11.5 ± 10.2
EDSS, median (range)	1.0 (0.0–3.5)	2.9 (0.0–8.0)	6.0 (2.5–8.0)	6.0 (1.0–8.5)	3.0 (0.0–8.5)
MSSS, median (range)	2.0 (0.2–7.3)	3.4 (0.0–9.8)	6.3 (1.3–9.0)	6.7 (0.8–9.6)	4.3 (0.1–9.8)

Demographic and clinical data were not available for all subjects.