Figure 2. . Urinary acetylamantadine concentrations in patients with lung cancer from the National Institute of Cancer Research & Hospital (Dhaka, Bangladesh site).

Acetylamantadine concentrations are shown for all types lung cancer and staging (A); Stage II (B); Stage III (C); and Stage IV (D). Urinary acetylamantadine concentrations were determined by LC–MS/MS technique at 2, 4 and 6 h postamantadine ingestion. Values are mean ± SEM and are expressed as ng/ml. The p < 0.05 was considered as significantly different versus healthy control group.

LC–MS/MS: Liquid chromatography–mass spectrometry/mass spectrometry;SEM: Scanning electron microscope.