Figure 3. . Urinary acetylamantadine concentrations in patients with different subtypes of lung cancer from the National Institute of Cancer Research & Hospital (Dhaka, Bangladesh site).

Acetylamantadine concentrations are shown for nonsquamous lung cancer (A); squamous lung cancer (B); adenocarcinoma (C); and small-cell lung cancer (D). Urinary acetylamantadine concentrations were determined by LC–MS/MS technique at 2, 4 and 6 h postamantadine ingestion. Values are mean ± SEM and are expressed as ng/ml. The p < 0.05 was considered as significantly different versus healthy control group.

LC–MS/MS: Liquid chromatography–mass spectrometry/mass spectrometry; SEM: Scanning electron microscope.