Figure 7. . Urinary acetylamantadine concentrations in patients with lung cancer from CancerCare Manitoba (Winnipeg site).

Acetylamantadine concentrations are shown for all types lung cancer and staging (A) and at Stage III (B), Stage IV lung cancer (C) and in adenocarcinoma (D). Urinary acetylamantadine concentrations were determined by LC–MS/MS technique at 2 and 4 h postamantadine ingestion. Values are mean ± SEM and are expressed as ng/ml. The p < 0.1 was considered as significantly different versus the healthy control group.

LC–MS/MS: Liquid chromatography–mass spectrometry/mass spectrometry; SEM: Standard error mean.