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. 2019 Feb 22;3(4):612–620. doi: 10.1182/bloodadvances.2018029199

Table 2.

Baseline characteristics of patients treated for newly diagnosed BL in Lilongwe, Malawi, by initial treatment regimen

Total no. of patients CHOP (n = 22) More intensive regimen (n = 9) P
No. % Median Range Mean SD No. % Median Range Mean SD
Male sex 31 15 68 6 67 1
Age, y 31 20 15-57 16 15-55 .65
Body mass index, kg/m2 26 18.9 4.9 17.9 1.5 .65
B symptoms 31 13 59 7 78 .43
Ann Arbor stage III to IV 31 18 82 6 67 .38
ECOG PS ≥2 31 13 59 3 33 .25
aaIPI 28 1
 1 5 24 2 28
 2 9 43 3 43
 3 7 33 2 28
Central nervous system involvement 31 5 23 0 0 .27
Bone marrow involvement 21 3 21 1 14 1
Abdominal disease 31 14 64 6 67 1
Bulky disease (>10 cm) 20 11 73 4 80 1
HIV positive 31 9 41 3 33 1
CD4 count, cells per μL 12 130 29-605 238 39-272 .78
HIV viral load, detectable >400 copies per μL 12 4 44 0 0 .49
White blood cells, ×109/L 31 7.2 2.8-20.3 7.4 2.1-11.7 .91
Hemoglobin, g/dL 31 11.0 1.6-14.8 9.9 7.7-11.7 .13
Platelets, ×109/L 31 314 139-859 438 157-635 .24
Creatinine, mg/dL 29 0.6 0.3-2.4 0.5 0.4-1.7 .41
Bilirubin, mg/dL 28 0.4 0.2-2.0 0.4 0.2-1.4 .72
Albumin, g/dL 22 3.7 2.7-5.8 3.4 2.3-4.4 .38
LDH ratio per ULN 28 2.2 0.4-20 2.2 1.0-5.1 .98
LDH >2× ULN 28 14 33 5 71 1.0