Table II.
Effects of r-hGH and exercise on physiological properties and metabolic parameters in rats.
| P-valuea | |||||||
|---|---|---|---|---|---|---|---|
| ------------------------------------------------------------------------------ | |||||||
| Parameters | SC (n=10) | SE (n=8) | GH (n=10) | SE-GH (n=9) | SE effect | GH effect | GH+SE effect |
| BW, g | 307.80±6.34 | 269.38±7.09 | 281.50±6.34 | 275.11±6.69 | <0.05 | 0.13 | <0.05 |
| HWI | 3.64±0.03 | 4.21±0.07 | 4.02±0.06 | 4.40±0.07 | <0.05 | 0.08 | <0.001 |
| LVWT, mm | 3.09±0.06 | 3.13±0.06 | 3.14±0.05 | 3.23±0.08 | 0.23 | 0.67 | 0.29 |
| Insulin, mIU/l | 0.68±0.13 | 0.44±0.08 | 0.58±0.12 | 0.57±0.11 | 0.89 | 0.29 | 0.34 |
| IGF-1, pg/ml | 5,736.05±306.62 | 6,410.46±226.46 | 6,260.12±202.55 | 5,922.10±142.87 | 0.69 | 0.97 | 0.23 |
Data are presented as the mean ± standard error of the mean. aCompared with SC. BW, body weight; HWI, heart weight index (heart weight/ body weight x1,000 g/g); LVWT, left ventricular wall thickness; IGF-1, insulin-like growth hormone-1; SC, sedentary control; SE, swimming exercise; GH, r-hGH exposure; SE-GH, swimming exercise-r-hGH exposure; r-hGH, recombinant human growth hormone.