Table 4.
Phenotypic and IgE analyses after in vivo DDAB treatments.
B-cells (% lymphocyte population) |
IgE+ B-cells (% total B-cells) |
||||
---|---|---|---|---|---|
Dose group | % | Cells (×106) | % | Cells (×105) | Total IgE (ng/ml) |
4 days | |||||
0% | 19.78 ± 1.45 | 0.56 ± 0.07 | 5.74 ± 0.71 | 0.31 ±0.02 | 4255 ± 758 |
0.0625 | 21.68± 0.58 | 1.02 ± 0.01 | 8.30 ±2.00 | 0.80 ± 0.02 | 3268 ± 645 |
0.1250 | 25.96 ± 0.73** | 2.71 ±0.26** | 12.51 ±2.14 | 3.46 ±0.75 | 3815 ± 295 |
0.2500 | 32.72 ± 1.35** | 4.26 ±1.38** | 19.01 ±4.33** | 8.91 ±2.93** | 3585 ± 872 |
14 days | |||||
0% | 22.56 ± 1.32 | 0.79 ±0.11 | 8.85 ± 1.23 | 0.70 ±0.01 | 4479 ± 556 |
0.0625 | 21.38± 0.70 | 1.48 ±0.17 | 18.92 ±3.91 | 2.96 ± 0.85 | 4510 ±532 |
0.1250 | 27.70 ± 0.65** | 3.69 ±0.36** | 13.99 ±2.155 | 5.10 ± 0.77** | 7226 ± 2238 |
0.2500 | 33.86 ±1.07** | 6.69 ±0.48** | 29.70±3.16** | 20.10 ±2.92** | 15 702 ± 4202** |
Levels of significance denoted as compared to vehicle (acetone).
p < 0.01
Values shown are means (n = 5)±SE.