Table 4.
Comparison of FOSQ and ESS scores at baseline to 1 year in patients with nonsleepy and sleepy OSA who used CPAP.
| Baseline | 1 year | Mean Difference (Baseline – 1 year) | P Value | |
|---|---|---|---|---|
| Non-Sleepy CPAP | ||||
| N | 35 | 35 | ||
| FOSQ (total) | 18.52 ± 1.6 | 18.58 ± 1.8 | −.10 (−0.69, 0.49)† | |
| Median | 19.0 | 19.1 | .873 | |
| Interquartile Range | 18.0–19.9 | 18.2–19.9 | ||
| FOSQ Subscales | ||||
| General Productivity | 3.81 ± .21 | 3.82 ± .33 | .169 | |
| Social Outcome | 3.86 ± .45 | 3.82 ± .48 | .785 | |
| Activity Level | 3.58 ± .45 | 3.63 ± .41 | .859 | |
| Vigilance | 3.74 ± .35 | 3.79 ± .37 | .361 | |
| Intimacy | 3.65 ± .55 | 3.50 ± .75 | .090 | |
| Sleepiness-Related | 22.9% (8) | 20.6% (7) | 1.00 | |
| Functional Impairment | ||||
| (FOSQ < 18) | ||||
| ESS | 5.4 ± 2.5 | 5.5 ± 3.2 | −.03 (−1.1, 1.05) | |
| Median | 6.0 | 5.0 | .860 | |
| Interquartile Range | 4.0–8.0 | 3.0–8.0 | ||
| CPAP Adherencea | N/A | 2.93 ± 2.93 | ||
| Median | 3.19 | |||
| Interquartile Range | (0–5.8) | |||
| Sleepy CPAP | ||||
| N | 45 | 45 | ||
| FOSQ (total) | 17.2 ± 2.0 | 18.15 ± 1.7 | −.89 (−1.5, −0.32)† | |
| Median | 17.67 | 18.75 | .002* | |
| Interquartile Range | 16.2–18.86 | 17.11–19.46 | ||
| FOSQ Subscales | ||||
| General Productivity | 3.66 ± .33 | 3.80 ± .21 | .016* | |
| Social Outcome | 3.81 ± .38 | 3.88 ± .30 | .160 | |
| Activity Level | 3.30 ± .54 | 3.53 ± .41 | .003* | |
| Vigilance | 3.31 ± .43 | 3.59 ± .30 | <.001* | |
| Intimacy | 3.12 ± .88 | 3.31 ± .92 | .101 | |
| Sleepiness-Related | 55.8% (24) | 40% (16) | .092 | |
| Functional Impairment | ||||
| (FOSQ < 18) | ||||
| ESS | 12.6 ± 2.5 | 9.4 ± 2.8 | 3.23 (2.2, 4.2) | |
| Median | 12.0 | 9.0 | <.001* | |
| Interquartile Range | 11.0–14.0 | 7.0–12.0 | ||
| EDS (ESS ≥ 10) | 100% (45) | 42% (19) | ||
| CPAP Adherencea | N/A | 3.0 ± 3.09 | ||
| Median | 3.09 | |||
| Interquartile Range | (0–5.11) |
Abbreviations: CPAP, continuous positive airway pressure; EDS, excessive daytime sleepiness; ESS, Epworth Sleepiness Scale; FOSQ, functional outcomes of sleep questionnaire.
Data are presented as % (n), mean ± SD, or median (IQR).
a
Data available for n = 35 nonsleepy and n = 44 sleepy patients.
†
Relative difference (1 year – Baseline / Baseline x 100) in FOSQ (total) between groups was found to be significantly greater in the sleepy OSA group compared to the non-sleepy OSA group after 1 year of CPAP use (6.1% versus 0.9%, respectively).