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. 2019 Feb 27;20:42. doi: 10.1186/s12931-019-1003-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Impact of genotype (WT and SmPparγ^−/−) and diet on the right (RV) and left ventricle (LV) remodelling and hypertrophy: a RV to LV + septum (S) ratios (= Fulton’s Index) from mice of each study group are shown at the 24 week time point (n = 8–15 per group). b Shown are representative hematoxylin-eosin stainings of the RV and the LV derived from all analyzed animal groups (scale bar = 50 μm). Large pictures were digitalized at × 40, insets are shown for better visualization. c Quantifications of the myocyte cross section area (in μm²) in the RV and LV in each study group (n = 16–50 myocytes / N = 4–5 animals). For a, c and d a two-factor linear model with interaction and a non-parametric Kruskal-Wallis test was performed