Fig. 6.

VDR decrease is associated with HIF-1α up-regulation in human oral biopsies. a and b Western blot analyses (a) of human oral epithelia lysates with antibodies as indicated, and densitometric quantitation of these data (b), N = normal; NI = non-inflamed; I = inflamed. c Immunostaining of sections of human oral samples. d Real-time PCR analyses of transcript levels of IFNγ and IL-1β in human oral epithelium. *P < 0.05, **P < 0.01, ***P < 0.001 vs. corresponding normal. Normal, healthy control; Non-inflamed, non-diseased tissue of OLP patients; Inflamed, diseased tissues of OLP patients. Normal, n = 7; OLP patients: n = 28