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Effects of virus on NKG2D expression
| virus | Mechanism | Function | Reference |
|---|---|---|---|
| HCMV | HCMV-miR-UL112 interferes with MICB mRNA | MICB↓ | [70] |
| JCV, BKV | JCV/BKV miR-J1/B1-3p interferes with ULBP3 mRNA | ULBP3↓ | [71] |
| HBV | HBc and HBx promote the expression of GATA-2 and GATA-3 | MICA/B↓ | [72] |
| HCV | NS3/4A protein | NKG2DL↓ | [73] |
| AdV | E3/19 K protein | NKG2DL stored | [74] |
| VSV | n.d | MEI | [75] |
| HIV | n.d | sNKG2DLs↑ | [76] |
n.d not determined, MEI membrane expression inhibition, ↓: decrease; ↑: increase
