Table 3.

Summary of moderator variables from the single and multiple meta-regression model for RER in response to hypoxic exposure during exercise matched for relative intensities

Moderator variable RER (relative) (n = 31)	p value	Comparison	Multiple regression p value
Pre-existing nutritional state	< 0.01	Fasted (n = 8, MD − 0.07, 95% CI − 0.09 to − 0.06) Fed (n = 18, MD 0.06, 95% CI 0.01 to 0.10)	< 0.01
Carbohydrate supplementation during exercise	0.22	Yes (n = 4, MD − 0.04, 95% CI − 0.09 to 0.01) No (n = 27, MD 0.02, 95% -0.02 to 0.06)	N/A
Exercise mode	0.60	Cycling (n = 26, MD 0.02, 95% CI − 0.02 to 0.05) Running (n = 5, MD − 0.01, 95% CI − 0.04 to 0.03)	N/A
Duration of hypoxic exposure	0.67	Acute (n = 22, MD 0.02, 95% CI − 0.03 to 0.06) Chronic (n = 9, MD 0.00, 95% CI − 0.03 to 0.04)	N/A
Type of hypoxia	0.96	Simulated normobaric hypoxia (n = 7, MD 0.01, 95% CI − 0.01 to 0.03) Simulated hypobaric hypoxia (n = 9, MD 0.00, 95% CI − 0.03 to 0.03) Terrestrial altitude (n = 15, MD 0.02, 95% CI − 0.03 to 0.07)	N/A
Percentage male	0.43	Meta-regression percentage male vs. MD (slope 0.0006, 95% CI − 0.0009 to 0.0021)	N/A
Exercise intensity	0.04	Meta-regression of exercise intensity vs. MD (slope 0.0033, 95% CI 0.0002 to 0.0065)	0.049
Exercise duration	0.78	Meta-regression of exercise duration vs. MD (slope − 0.0002, 95% CI − 0.0018 to 0.014)	N/A
Altitude height	0.90	Meta-regression of altitude height vs. ES (slope − 0.00, 95% CI − 0.00 to 0.00)	N/A