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. 2019 Feb 20;6:38. doi: 10.3389/fvets.2019.00038

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Copyright © 2019 Montaner-Tarbes, del Portillo, Montoya and Fraile.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genome structure and mature viral particle of PRRSV virus. (A) Non-structural proteins are located in the 5′ end of the genome, codifying for two different polyproteins pp1a and pp1ab that are cleaved into at least 14 nsps (nsp1 to nsp12 and nsp1α and nsp1β, and nsp7α, and nsp7β). Structural proteins located near the 3′ end, are associated to the viral envelope and RNA packaging. (B) PRRSV mature viral particle, composed of a lipid bilayer envelop with viral receptor glycoproteins involved on infection and cell internalization. Single stranded positive RNA is associated with nucleocapsid protein in the internal layer of the virus.