Table 3.

Univariate and multivariate analyses of survival in patients with PNETs.

Characteristic		OS						CSS
		Univariate analysis			Multivariate analysis			Univariate analysis			Multivariate analysis
		HR	95% CI	P	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Age (years)	≤60/>60	1.77	1.59–1.96	<0.001	1.58	1.30–1.93	<0.001	1.72	1.55–1.91	<0.001	1.49	1.21–1.83	<0.001
Gender	Female/male	1.06	0.96–1.18	0.254			NI	1.08	0.97–1.20	0.156			NI
Surgery	No surgery/surgery	0.30	0.25–0.37	<0.001	0.24	0.10–0.62	0.003	0.29	0.24–0.36	<0.001	0.25	0.10–0.65	0.005
Surgery	No/recommended, but no/surgery	0.58	0.53–0.63	<0.001	1.20	0.75–1.92	0.438	0.56	0.52–0.62	<0.001	1.18	0.73–1.91	0.494
Tumor site	Head/body/tail	1.009	0.98–1.05	0.599			NI	1.00	0.97–1.04	0.837			NI
Tumor grade	Well/moderately/poorly	1.91	1.75–2.09	<0.001	1.83	1.66–2.03	<0.001	1.92	1.75–2.10	<0.001	1.85	1.67–2.05	<0.001
Tumor size	≤4 cm/≥4 cm	1.03	0.93–1.14	0.621			NI	1.01	0.91–1.12	0.893			NI
T stage (8th)	T1/T2/T3/T4	0.98	0.90–1.07	0.645			NI	0.98	0.90–1.06	0.564			NI
LN metastasis	Absent/present	0.87	0.79–0.96	0.005	1.05	0.89–1.25	0.549	0.86	0.78–0.95	0.002	0.87	0.85–1.21	0.868

HR, hazard ratio; NI, not included; other abbreviations as in Table 2.