Table 2:

Risk Factors for Ventral Hernia in First Year after Surgery

			Univariate			Multivariatea,b
Variable		% with Hernia	Relative Risk	95 % CI	P-value	Relative Risk	95 % CI	P-value
Race	Other	14.3	1.5	(0.39 – 5.7)	0.64
	White	9.6
Diabetes	Present	7.7	0.77	(0.19 –3.1)	1.000
	Absent	10.0
Nutritional Status	Deficient	31.9	60c	(8.2 – 434)	<.001	48	(14 –164)	<.001
	Normal	0.5
Cancer Stage	Late	9.6	0.94	(0.43 – 2.1)	0.83
	Early	10.3
Histology	Serous	9.6	1.1	(0.46 – 2.4)	1.000
	Other	9.1
Pathology Grade	3	10.1	1.1	(0.44 – 2.9)	1.000
	1 or 2	8.9
CRS	Sub-optimal	28.6	5.1	(2.5 – 10)	<.001	4.3	(2.5– 7.3)	<.001
	Optimal	5.6
Fascia closure	Other	15.0	2.0	(0.96 – 4.1)	0.073
	Running	7.6
Chemo Mode	IP	8.3	0.79	(0.12 – 5.4)	1.000
	IV	10.5
Surgical Site Infection	Present	21.9	2.7	(1.2 – 5.9)	0.024	1.4	(0.78 – 2.5)	0.25
	Absent	8.2
Age	≥ 65 yrs	5.7	0.48	(0.19 – 1.2)	0.13
	< 65 yrs	11.9
BMId	Obese	17.2	3.2	(1.5 – 6.8)	0.003	1.4	(0.81 – 2.3)	0.25
	Non-obese	5.4
EBL	≥ 800 mL	11.8	1.3	(0.61 – 2.8)	0.50
	< 800 mL	9.0

^aModel included nutritional status, CRS, surgical site infection, and BMI as well as adjustment for fascial closure and age.

^bThe multivariate analysis column contains empty cells because only variables with p<0.05 on univariate analysis were tested in the model.

^cBolded values represent those significant at p<0.05.

^dObese = BMI ≥ 30 kg/m²; Non-obese = BMI < 30 kg/m²

Abbreviations: CRS = cytoreductive surgery, BMI = body mass index, EBL = estimated blood loss