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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Mult Scler Relat Disord. 2018 Nov 13;27:315–323. doi: 10.1016/j.msard.2018.11.010

Figure 4. Optic Nerve DTI measurements.

Figure 4.

Left, pseudocolored representative images showing the diffusion changes in 8 week EAE mice relative to controls. Left and Right optic nerves are shown in coronal section and indicated by white arrows in FA maps. Diffusion maps for TR, AD and RD are shown in enlarged views below; ON ROIs are shown in black boxes. Right, quantified ON diffusion changes across the time-course. **, p<0.01, ***, P<0.001, ****, p<0.0001