Figure 2.

Characterization of photoresponsive RGD peptide conjugation in 3-D HA-APP hydrogel. (A) IR spectrum of alkoxylphenacyl-based polycarbonate (APP) nanocarrier before and after RGD peptide loading. (B) UV spectrum showing change in absorbance with increasing photodegradation time. (C) IR spectrum of photo-controlled RGD peptide conjugation onto HA-Ac Macromers with increasing, one-time UV exposure. (D-F) Kinetics of RGD peptide conjugation to HA-Ac macromers based on RGD peptide release profiles for (D) constant UV exposure, (E) one-time UV exposure, (F) and periodic UV exposure times. Error bars represent ± S.E.M. from 3 independent experiments. P-values were calculated using the Student’s t-test. *, P < 0.05.