Table 2.
Adjusted Regression coefficients (β)a for associations between prenatal growth measuresb and maternal serum concentrations of PCB-118, PCB-153, and PCB-187 in a sample of British girls.
PCB-118 | p-value | PCB-153 | p-Value | PCB-187 | p-Value | |
---|---|---|---|---|---|---|
Birth length c(cm) (n = 363) | ||||||
Unadjusted β (95% CI) | 0.12 (−0.16, 0.41) | 0.39 | −0.04 (−0.12, 0.04) | 0.30 | −0.34 (−0.72, 0.05) | 0.09 |
Multivariate β (95% CI) | 0.08 (−0.21, 0.36) | 0.60 | −0.04 (−0.12, 0.04) | 0.29 | −0.33 (−0.73, 0.06) | 0.10 |
Ponderal Index d(n = 357) | ||||||
Unadjusted β (95% CI) | −0.03 (−0.06, 0.01) | 0.10 | −0.01 (−0.01, 0.00) | 0.24 | −0.02 (−0.07, 0.02) | 0.30 |
Multivariate β (95% CI) | −0.03 (−0.06, 0.01) | 0.10 | 0.00 (−0.01, 0.01) | 0.97 | 0.00 (−0.04, 0.05) | 0.91 |
Gestational agee (wks) (n = 444) | ||||||
Unadjusted β (95% CI) | 0.02 (−0.15, 0.18) | 0.85 | −0.01 (−0.06, 0.04) | 0.72 | −0.12 (−0.37, 0.13) | 0.35 |
Multivariate β (95% CI) | 0.02 (−0.15, 0.18) | 0.82 | −0.01 (−0.06, 0.04) | 0.80 | −0.11 (−0.36, 0.14) | 0.38 |
Per 10 unit (ng/g lipid) increase in analyte. In multivariate models maternal pre-pregnancy BMI, and gestational age at maternal sample collection were entered as continuous variables (rather than categorical as presented in Table 1).
For birthweight, significant interactions were observed with educational status; thus, final stratified results for birthweight are provided in Table 3.
Adjusted for sampling design, previous births and maternal pre-pregnancy BMI.
Adjusted for sampling design, previous births, maternal pre-pregnancy BMI, maternal tobacco use during pregnancy.
Adjusted for sampling design, gestational age at maternal sample collection.