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PGC-1α dissociates target gene promoters in the failing heart. (A) Schematic representation of PGC-1α target gene promoters. (B-C) The promoter occupancy of PGC-1α in the target gene promoters in the PO model (B) and PGC-1α-cKO mice (C). The numbers of mice examined in each experimental group were: 4–6 (B and C) and 4–6 (D). * p<0.05; ** p<0.01 as indicated.
